SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46b39ee9433d6d58221b45fe7e4fc9fd5fc53870b33904352c372bd1f82c72ac' 
  AND token = 'RB9NS+l49V44MjenTtCJn2C/WmsHIbfkY44N3qnq3GE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}