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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7486ea7f7f69264f00f7ab1dcca987fce13a53ffa4274a49e92a7df0f67a8399' 
  AND token = 'EZxe71ZHabsR57rsBSjTLWXfRtFcfUVuiiOANBQL6Sc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}