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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '816aef29351cac1d58517666ab44ca783a471bc48a2968a5d2d26769bccd38c7' 
  AND token = 'zilX8bN+2Nq7VzUPwToxBsMrCqZu3Zz/3hcShuabBN8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}