SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d8d1900947bfaa377af29828d09d3b79aa005f483ea12a76146aebd5564622a' 
  AND token = 'ZJLbIyoEM4ccKGXkqDPJ4xrTQJIMalQ3lBFR15Ey16c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}