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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72dd2cd3c54efaab1f3cd21caaa8df3e36465e3f4e983d6c7a7bd6a57b559b8c' 
  AND token = 'TJaMUqgrypFp6jnzuAW/B30b+YiLvbt5Gk7mS5p7N3k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}