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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '17d33b44ffe4c08b3ed4951bf60eaf7592dd9b365f341cba3857d9e2e3f05272' 
  AND token = 'bmemMy105Pi8vZO8e4/kHO0GsmcLJNdkwv1cJGG0x1k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}