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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c16e547bb5948bf947036552a584af14ff92e4e1f2264c6839b0b0d53ed5c00' 
  AND token = 'oRbKDZgYO+VDxovF5psZAU5EWwv4dGP368cKFuvsIxk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}