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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e733489561d910229482243019fd0fe7b9d44c579f536c77b20ce5e63ec43e9' 
  AND token = 'nkoIFr2376dLG/ltzZRZe2eAWr0YgT/JHjGIx5qL+t0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}