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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e21a764867307a1bdb7e0c1630339e400d03bee3f784781a2cea712f6f9ec76' 
  AND token = '/isPYMercSQBVnpTqpLeDNfuURuJM1pHAkzMDz/a6eE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}