SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '183a9c14ae587eb931ec0ba78f8117e2e12c8206363225a895bb36e06f3e5c5b' 
  AND token = '/GCkGVdRXAyhdRW/DgFeHjj0HB9l/rjXZs1HrCFy+mo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}