SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '677f9d78c212c0ac113f28208da8b29398b892c1716a46a137f443240c19a681' 
  AND token = 'O1V/tirD8lkrVvbqftnjUYkcY4jN725xsaARsHE8kjI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}