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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ad44e739de78c9278d827a9abda29fbb5c7b58aaaa030f5134bcbbe797301df' 
  AND token = 'Qsb/ijHG6qSN4nb85c0xwnboM/s533delDryPAoBEGQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}