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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a123108565aa84bc321b50c2daf9b3a786147c88da633ae38a0ab855c7c6c9cc' 
  AND token = 'o/0t2Qu8ekh8guHmAzXFuMBtn31QCgDTG5RAjk2Zed4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}