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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49060d03822d8b385e6ed1ebc23e32aa6a77cba9b9f9ec5749991ece1a1b2985' 
  AND token = 'NXGr5FSfaDKjcsy/k2GTDp0d+hyNjWLg6uJE26SyGaU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}