SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '546b547ef36ee3b0e2e4beb9e2a5ddd9c60053413269938aadd10259992d5ac5' 
  AND token = 'GSn3tEa7NR4qceL33lx9G/IVmpHD98o0xh8BE2W46tg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}