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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3fcbd8c71edd22bcdadff54e5c8aeaec82c15b4a7bc60c000c2d9ffcfab0bc98' 
  AND token = 'uTnpSuw+mb4vQ3SJFm7rZ1jf2I5EzaYAVFqnNexnCxg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}