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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5da91da14d2a5bb54530b411a80241c6bf5011a7e00a622ee21307f105b27789' 
  AND token = 'oci1LZSuyqgZ6YBMWej+rQRNTKM5N/iNWiIp0zHlJvA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}