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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9484e4404c349ab3d0d97174d8f9a0d84bf5bbf194caac7574833978c917caa8' 
  AND token = 'D0PBHrsO/sKj/EqRTUqR1Upa0tDiw1xqi9dSAFcYpMU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}