SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '989e0b2e44a72960d9358bbff2921305987a83753ba15f7f107ec5ba0db8a623' 
  AND token = '11/6sObgniT2GFrEwJHgT6qMvZzpMajQH7AW0wanF3Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}