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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eeb3a7b2372d0b92228fda94b675d56d6d1386af85005a93d44535a54efdefa3' 
  AND token = '3mJGNV7LJskBEOix9gNl3SPN9m3FDGQ7VZtId0AQ/Zo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}