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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c5ad9cd89f7d2c1fd50207df572a7e87e425d31b5250e8a21e664b4db7476ce' 
  AND token = 'IvKdByvw4GlTFCUoAO9TTh9/pG9USQ1T7HpyUTHTkrg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}