SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e38f262b3c8058235a65649c982d121cb58d5c800396c981af37eb200c26112' 
  AND token = 'jJRjVDDI8Ppy3alxfw9WI1yv6ZVKnT3D1e40Obzk1JQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}