SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe661aa7f523a2e29d881070381361dc8ff0bd3c945d4a121c414adc46e1a455' 
  AND token = 'S/Z1jaEvZ7GI1Xv30hYucb390YMSKYux04zuzBElXgo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}