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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5877d109254c46ff4b241d2cefdade610f1668feb2cae9d74bc83d8d688be2a1' 
  AND token = 'hE4zvz76sNCTa87LkLmLU+6SyEZ+ztKlmCuLaxCvRPo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}