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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c3182de6e151f4da1a2f03c3e494a22e779d285ce866f4e4c6bf3a6a0d18629' 
  AND token = 'gu8+WmOEbIQJm0RcEpPN2on+7q9rtJy1b4Svj6fJxJU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}