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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1efe2c02377a4a20ca3a4390dfce09abc4500782d3b315c37f4fd54860bfa52c' 
  AND token = '0/4JOcdIb50HLsz9ywYIOD0dPLDQnQ50qUrow7LVPdw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}