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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '17e5fb3fb5d72b12027bf01173f3b38ec0be145ed2e09354faac1f6b295a11a0' 
  AND token = 'Jyl+HkLtsU9nrl1f9PE0/lklmKNIeerYnSTD0Dgmdsc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}