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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '288757c15c4201ab5b1cc50c78fd08aea8f4d9ff0b0f3a22e3b06e32db5fc922' 
  AND token = '4wYGeFl4bFMFC+0+fxL5dfFaI5qfBJJ38OMgDrrb/TI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}