SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b1b12c46ded198be5710cf6f76e52b0593e2a50799b00941753015970d1b08d4' 
  AND token = 'qMF604u7Jgw3PMWXplt2ae6KNImebw3kyTISPI+tBXE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}