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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8614c9aed1fdc8a74df0707ecb166b3e4ba40fc2e4856b6885cf37c27d815e09' 
  AND token = '7aqJWfiiXubvP34o5vacE/fQzFVXG3aJycHdfFA54jI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}