SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c2fa554dab42faffb488705426e267669dc405f44861027bf44d060189a350c' 
  AND token = '4k7NO7ss0hkVOSNXfAXbYp145PzrDrTfXOeVL9LdC/0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}