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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3929298892c3329f8298c4d27ad873b5ebd11f06c074244e1450281254164a86' 
  AND token = 'aIiFOSb9MXP2u298pkwrDJqTeJWzcA+ezNwVez+5ktg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}