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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d6d747d52823069d8c498cb62a3e60cca02b5ef4f81386be05ed8127e2320f3' 
  AND token = 'ZomHTQlRW8Cq801VX27CnSKSt+mx4QN2qARlX5ruPU0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}