SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fd85573648e257aac95854509aa3271491df2137638eed503aceae0539001359' 
  AND token = 'mJpFXWYRanvL7tienjbnLTi3yQM83E59SGHfE+RZV0U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}