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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '99a8ad9de8a0dd86c2538f244cb2cb813cf7cc677ee1ec47efe12275d3e3b61a' 
  AND token = 'mQAxqgD0R+d6HFNy5xBIH53dHbcL0DrwpVKGMUd7YcY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}