SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fdff42e7ca8d1cba9ebebcc961aed7f9d74d0d5554315b13d609814d12bf7d88' 
  AND token = '+f25zCPtgPMC/0D6L4D+04t5uthWfblEmwnA9rRuofk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}