SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '06274a3d879264f68607387fdd48415c98cf16fcd2da9f6e934c05c41e9a485d' 
  AND token = 'Vlwj/ZiFY20AT1vw3Tfo0bgoQfVbNuP5cuNxF0Z//MI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}