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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad805b3f9b81c29704e2fc69511af4f9ab08ffb081c2daaf0322a0b56c9cf163' 
  AND token = 'u/XJHe/xDhEPLFEhPYFkRAlekEpj2blKD18vy9LH40M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}