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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e889ea6212efd5288aded0671ec58bb562f5af52346a74254f4762d8208e46bd' 
  AND token = 'GAEI0HIWJjD3Wn1URGX5urxkzBJ80X+e/tM1ZvMCbc8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}