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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46a1197557f65780c7a6afe124e98d36dfb28d152188b3bcbd5562c1c0d53103' 
  AND token = 'tKXeunBYf7he1n4Gav+dYF1mhhe3JWqQTJ3Ap0NkPR0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}