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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd5291e8c073e082cf7ef5ed64144f7c3718998b56343ab1c5daa3b4dd3ab0f68' 
  AND token = '8tA741/NqsYpVfTd4v2VcLsXLZl4JzJAqm0rC4TMTe0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}