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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e169e1f1b1fec7f49a58ff2c9bd449668746ce65c67ab2ab8593e4cfdcb9baf6' 
  AND token = 'bEq6UW3xtW22WU0RuKWwdaEA9jMUOwGuW0dNhdMJfj0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}