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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e331a49711ec1d34deb85c20a400f92f7315c2be32518c80abbb1059cfafe1fc' 
  AND token = 'qtvxJPB4DTwdNUEQ4nLiSBuHR8s0vx9oVbUP6AOIzBE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}