SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cdfd1d926c2cea20d033ae925de06bce32f1b92113c871a31b53ca075d2aee60' 
  AND token = 'jzguiBUlvwkWAeP+vDESdqJM8hBnmIGteQJv1bIqi0g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}