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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea726e2280bf85beb63f4498a0fb93137156ddbad9938a5285fd0b2870cbbd72' 
  AND token = 'zk5TFJ4w6meQx2IM4U8r3nt6oVLlWqhPXAq7Dk0Z0VI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}