SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '881ccf09da6b853ce42e56d071f93faddd2dffc243e0b552c12f2055845e4254' 
  AND token = 't9NR5UTDIP9LykFECxrJCQcI5xF0gdaIcVS3OeDwfkY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}