SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ceed194ee4c3a51f68d9fed9a57d72c8208dad4d9804bf1ced9867e3b710b24' 
  AND token = 'luBC0nvNXSazqrdT6Xp7Hd4kxYtwzBRdxSm+Y64BWow=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}