SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d88ded4ebf8e474697986ec0184336149dd1dea7d8a9a57583ae09885c9df7b' 
  AND token = 'QUAfEpfNX6oxk2xRG/tULIN+zwkCIQfEoHKgUi1hRRQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}