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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '194f7c4a83433eda31682a7baf32939b7efc089af531f39a24669fd9bfac7ce7' 
  AND token = 'R2y/wksFok/lBR0d4/rx4Q+JlLd3t+vq6wEaWkJq7Js=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}