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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '290bb928a1021472446c139d4190ffbb666c32d6fcb6a9db4940193236378864' 
  AND token = 'bzuowhefGGRoe7jcxgaQsDFAGowE05+CTxv1pCgrY4c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}